Description of the drug Polygot
Description of the drug “Polygot” on this page is a simplified and amended version of the official instructions for use. Before buying or using the drug, you should consult your physician and read the manufacturer’s approved leaflet. The information about the drug is for information purposes only and must not be used as a guide for self-medication. Only your physician can decide whether to prescribe this medicine and determine the dosage and how to administer it.
Indications for use of the drug Polygot. Acute attacks of migraine and similar attacks of headache of vascular genesis. Polygot should be taken at the beginning of an attack. For the first use a dose of 2 tablets is recommended. If there is no improvement after 30 minutes, take 1 tablet more. The drug can be repeated further at 30 min intervals, not exceeding the maximum daily dose. In subsequent attacks, the initial dose can be increased to 3 tablets, depending on the total dose taken during the previous attacks. The maximum daily dose is 6 mg ergotamine tartrate (6 tablets). The maximum weekly dose is 10 mg ergotamine tartrate (10 tablets).
Side effects. Nausea, vomiting, allergic reactions, increased blood pressure. After long-term use, weakness and pain in the extremities, tremor, cardialgia, tachycardia, bradycardia, fibrotic changes in the pleura and retroperitoneal space. Overdose. Symptoms: drowsiness, confusion, tachycardia, dizziness, paresthesia, respiratory center depression, coma. Treatment: gastric lavage, activated charcoal, symptomatic therapy.
Contraindications: hypersensitivity to one of the drug components; peripheral circulation disorder; obliterating vascular diseases; severe arterial hypertension; hepatic or renal failure; sepsis; pregnancy, lactation.
Special indications. If symptoms such as numbness of fingertips or feet occur, the drug should be stopped immediately and the patient should consult a physician. Polygot is used to treat an acute migraine attack; it should not be used to prevent attacks or taken frequently over a long period of time.
Symptoms: nausea, vomiting, drowsiness, confusion, tachycardia, dizziness, parasthesias and pain in extremities, respiratory depression, coma.
Treatment: gastric lavage, activated charcoal intake, symptomatic therapy, at atrial spasm – vasodilators such as sodium nitroprusside.
Drug interaction with other drugs. Concomitant administration of oleandomycin, erythromycin, or josamycin together with ergotamine may result in increased plasma concentrations of ergotamine.
There are reports of several cases of vasospasm in patients receiving ergotamine and propranololol simultaneously.
Drug storage conditions. At room temperature in a light-protected place.